cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide
HEXADECYL[2-([P-METHOXYBENZYL]-2-PYRIMIDINYLAMINO)ETHYL]DIMETHYL-AMMONIUM BROMIDE
CAS: 553-08-2
Molecular Formula: C32H55BrN4O
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide - Names and Identifiers
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide - Physico-chemical Properties
| Molecular Formula | C32H55BrN4O |
| Molar Mass | 591.71 |
| Melting Point | 91-92° |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Inert atmosphere,Room Temperature |
| In vitro study | Thonzonium bromide inhibits RANKL-induced OC formation, the appearance of OC-specific marker genes and bone-resorbing activity in vitro. Thonzonium bromide blocks the RANKL-induced activation of NF-κB, ERK and c-Fos as well as the induction of NFATc1 which is essential for OC formation. Thonzonium bromide disrupts F-actin ring formation resulting in disturbances in cytoskeletal structure in mature OCs during bone resorption. Thonzonium bromide exhibits protective effects in an in vivo murine model of LPS-induced calvarial osteolysis. |
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 2933599550 |
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.69 ml | 8.45 ml | 16.9 ml |
| 5 mM | 0.338 ml | 1.69 ml | 3.38 ml |
| 10 mM | 0.169 ml | 0.845 ml | 1.69 ml |
| 5 mM | 0.034 ml | 0.169 ml | 0.338 ml |
Last Update：2024-01-02 23:10:35
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide - Reference Information
| biological activity | Thonzonium bromide, an antibacterial agent structurally similar to Farnesol (HY-Y0248A), A monocationic surfactant that inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. Thonzonium bromide inhibited proton transport in a dose-dependent manner (EC50=69 μm). |
Last Update：2024-04-09 21:04:16
![cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide](http://res.chembk.com/assets/str/2d/5/55/553-08-2.png)
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View History
cetyl-dimethyl-[2-[p-anisyl(2-pyrimidyl)amino]ethyl]ammonium bromide
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吡咯-2-硼酸频哪醇酯
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2-羟基-5-甲基苄醇
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-(7-溴-1-氧亚基-2,3-二氢-1H-异吲哚-2-基)哌啶-2,6-二酮
过钌酸四内胺
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2-METHYL-2-PROPANYL 4,4,4-TRIFLUORO-3-OXOBUTANOATE